Hu, Yu Polycystic Kidney Disease

ISBN: 978-1-138-60389-9

Auflage: 1st Ed.

Erscheinungsdatum: November 2019

Einband: Hardcover

Seitenzahl: 360 p.

Illustrationen: 50 ill.

Verlag: CRC Press

117,00 € *

Lieferzeit ab Ihrer Bestellung: 2-14 Tage je nach Lieferbarkeit und Verlag

Beschreibung

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies.

Explores the role of cilia in polycystic kidney disease
Focuses on myriad state-of-the-art methods and techniques
Reviews specific mutations integral to this autosomal genetic disease
Includes discussions of model systems

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Hu, Yu Polycystic Kidney Disease

Beschreibung