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Dwivedi, Agarwal, Ray, Tripathi Skin Aging & Cancer

Ambient UV-R Exposure

ISBN: 978-981-13-2540-3

Erscheinungsdatum: Dezember 2019

Einband: Hardcover

Illustrationen: 35 ill.

Verlag: Springer

Lieferzeit ab Ihrer Bestellung: 2-14 Tage je nach Lieferbarkeit und Verlag

Beschreibung

  • The book  highlights the correlation between UVR-mediated skin aging and cancer
  • It covers the molecular mechanisms that lead to changes in the stem cell function during aging
  • It distinctively reviews bioinformatics tools used in elucidating the molecular mechanism underlying skin aging
  • It features various cutting-edge studies on UV-R induced melanin chemi-excitation and melanoma pathogenesis

This book summarizes the potent effect of ultraviolet radiation (UVR) on the photoaging and cancer formation. Skin is the largest human organ which continually reconstructs itself to ensure its viability, integrity, and ability to provide protection for the body. This protection can be compromised by the aging of the skin which ultimately promotes skin inflammation, impaired wound repair, and increased risk of skin cancer. The book entails mechanistic insights into the UVR-induced immunomodulation and DNA damage in the skin to delineate the pathogenesis, and develop novel ways for prevention of photoaging of the skin cells. It also elucidates the potential of nanotechnology in the treatment of skin cancer. Further, it discusses the bioinformatics approaches to understand the molecular mechanism of photoaging and cancer formation.