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Dietel, Wittekind, Bussolati, von Winterfeld Pre-Analytics of Pathological Specimens in Oncology

ISBN: 978-3-319-13956-2

Auflage: 1st Ed.

Erscheinungsdatum: Februar 2015

Einband: Hardcover

Seitenzahl: 133 p.

Illustrationen: 65 ill.

Verlag: Springer

Lieferzeit ab Ihrer Bestellung: 2-14 Tage je nach Lieferbarkeit und Verlag


  • Offers guidance in how to optimize the pre-analytical handling of tissue and improve diagnostic quality
  • Discusses the importance of cold ischemia time  
  • Examines the value of vacuum-based preservation and two-temperature fixation
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.?